PTU - Polskie Towarzystwo Urologiczne
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ASSESSMENT OF THE VALUE OF TISSUE POLYPEPTIDE ANTIGEN (TPA) IN THE PLASMA OF PATIENTS TREATED FOR PROSTATIC CARCINOMA
Article published in Urologia Polska 1987/40/4.

authors

Jan Kulpa, Antonina Marczyńska, Jan Leńko, Marek Pawlicki, Andrzej Bugajski
Z Zakładu Analityki i Biochemii Klinicznej Centrum Onkologii
Instytutu im. M. Skłodowskiej-Curie, Oddział w Krakowie
Kierownik: prof. dr hab. med. A. Marczyńska
Z Kliniki Chemioterapii Centrum Onkologii Instytutu im. M. Skłodowskiej-Curie, Oddział w Krakowie
Kierownik: doc. dr hab. med. M. Pawlicki
Dyrektor: prof. dr hab. med. J. Skołyszewski
Z Kliniki Urologii Akademii Medycznej w Krakowie
Kierownik: prof. dr med. J. Leńko

summary

In 71 patients treated for prostatic carcinoma the plasma !evel of TPA was determined before the treatment and serially after the operation assessing the value of this method as a supplementation of PAP determination. Initially raised plasma TPA level was observed in 36.6% of patients with prostatic carcinoma. A fairly far-reaching agreement was observed between TPA level and the clini­cal course, which was, however, much lower than for PAP. TPA determination was of certain Prognostic value since a higher proportion of positive results of the test was observed in the group of patients dying within two years. In about 80% of dying patients the concentration of at least one of these markers was raised.

references

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