ASSESSMENT OF THE VALUE OF TISSUE POLYPEPTIDE ANTIGEN (TPA) IN THE PLASMA OF PATIENTS TREATED FOR PROSTATIC CARCINOMA Article published in Urologia Polska 1987/40/4.
authors
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Jan Kulpa, Antonina Marczyńska, Jan Leńko, Marek Pawlicki, Andrzej Bugajski
- Z Zakładu Analityki i Biochemii Klinicznej Centrum Onkologii
Instytutu im. M. Skłodowskiej-Curie, Oddział w Krakowie
Kierownik: prof. dr hab. med. A. Marczyńska
Z Kliniki Chemioterapii Centrum Onkologii Instytutu im. M. Skłodowskiej-Curie, Oddział w Krakowie
Kierownik: doc. dr hab. med. M. Pawlicki
Dyrektor: prof. dr hab. med. J. Skołyszewski
Z Kliniki Urologii Akademii Medycznej w Krakowie
Kierownik: prof. dr med. J. Leńko
summary
- In 71 patients treated for prostatic carcinoma the plasma !evel of TPA was determined before the treatment and serially after the operation assessing the value of this method as a supplementation of PAP determination. Initially raised plasma TPA level was observed in 36.6% of patients with prostatic carcinoma. A fairly far-reaching agreement was observed between TPA level and the clinical course, which was, however, much lower than for PAP. TPA determination was of certain Prognostic value since a higher proportion of positive results of the test was observed in the group of patients dying within two years. In about 80% of dying patients the concentration of at least one of these markers was raised.
references
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