authors
-
Agnieszka Mikucka 1, Eugenia Gospodarek 1, Marzena Paprzycka 2
- 1 Katedra i Zakład Mikrobiologii, Akademia Medyczna im. L. Rydygiera w Bydgoszczy
Kierownik: prof. dr hab. n, med. Z. Dudziak
2 Zakład Mikrobiologii, Samodzielny Publiczny Wojewódzki Szpital im. dr. J. Biziela w Bydgoszczy
Kierownik: mgr J. Kochanowska
keywords
-
urinary tract urinary tract infections Corynebacterium urealyticum
summary
- Objectives. Corynebacterium urealyticum (formerly Corynebacterium group D2)
- was first described by King in 1972. Its role as a urinary tract pathogen is well
- established, particularly in patients who develop nosocomial infections
- following urologic manipulations and antibiotic therapy. C. urealyticum, like C.
- jeikeium, is resistant to many antibiotics with the exception of vancomycin and
- teicoplanin. This bacteria is a fre±uent component of the skin flora, particularly
- in hospitalized patients. C. urealyticum is a opportunistic pathogen. It has been
- involved in bacteraemia, endocarditis and more rarely other systemic infections
- such as pneumonia, peritonitis mostly in compromised hosts. In the work we
- analyzed infections occurrence and antimicrobial susceptibilities of C.
- urealyticum.
- Material and method. The subject of the examination were 26 of C.
- urealyticum strains. The strains were isolated from the clinical samples (urine,
- drain, blood, wound swab) of a nosocomial patients. All the samples were
- incubated on Columbia Agar supplemented with 5% sheep blood at 37°C in
- 5% CO2 for 24-48 h. Strains were identified by using the API Coryne system.
- The activities of the antimicrobial agents were determined by an agar dilution
- method with Mueller-Hinton agar which was supplemented with 5% sheep
- blood.
- Results. Most of the strains (73%) were isolated from the urine of bacteriuric
- patients. From drain, blood, wound swab were isolated, proportionally: 15%,
- 8%, 4% stains. Seventy seven percent of patients were above 65 years old. All
- strains were resistant to trimethoprim/sulfamethoxazole, nitrofurantoin. The
- bacteria were uinformly susceptible to yancomycin, teikoplanin; irregularly
- rare
- Conclusion. C. urealyticum is a opportunistic, multiresistance organism. Most
- often it has been involved in urinary tract infections. The bacteria cannot be
- disregarded in the course of diagnostic procedure. Their recognition is necessary
- for optimal preventive and therapeutic care of patients in risk groups.
references
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