PTU - Polskie Towarzystwo Urologiczne
list of articles:

CODE: 8.1 - Inflammatory myofibroblastic tumors of urinary bladder (pseudosarcoma) - case report
Article published in Urologia Polska 2006/59/Suplement 1.

authors

Paweł Dębiński 1, Elżbieta Górzyńska 2, Zdzisław Woźniak 3, Janusz Dembowski 1, Michał Wróbel 1, Bartosz Małkiewicz 1
1 Katedra i Klinika Urologii i Onkologii Urologicznej AM we Wrocławiu
2 Zakład Patomorfologii Szpitala Wojewódzkiego im. J. Babińskiego we Wrocławiu
3 Katedra i Zakład Anatomii Patologicznej AM we Wrocławiu

summary

Introduction. Pseudosarcoma is rare, benign, proliferative lesion, consists of spindle myofibroblastic cells. This tumor can easily be mistaken for a malignant neoplasm both clinically and histologically. The most frequent locations of the tumor are lungs, soft tissues, alimentary tract and also urinary tract. In urinary bladder it occurs mainly in young adults and children, predominantly in women.
Objectives. We describe 2 clinical cases of inflammatory myofibroblastic tumors localized in urinary bladder wall.
Materials and methods. Both female patients (age 19 and 14 yrs) presented symptoms of haematuria, dysuria, urgency. Cystoscopy revealed extensive, solid lesions with ulcerations. Primarily on the basis of histological studies of biopsy specimens poorly differential malignant neoplasm - leiomyosarcoma, infiltrative muscular wall of urinary bladder was diagnosed. In both cases radical cystectomy with creation of an orthotopic ileal neobladder was performed. After precise analysis of the postoperative specimens with application of immunohistochemical studies, finally in both cases inflammatory myofibroblastic tumors were diagnosed.
Results. On the basis of literature's review concerning prevalence of pseudosarcoma's cases, modalities and effectiveness of treatment, it seems probable that organ-sparing, simple excision is sufficient proceedings.
Conclusions. Pseudosarcoma should be taken into consideration in differential diagnosis of sarcomatous tumors. By recognizing the existence of this lesion, possible extensive and inappropriate surgery may be avoided.