authors
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Paweł Wiechno, Małgorzata Sadowska, Beata Paluchowska, Tomasz Demkow
- Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curic w Warszawie. Klinika Nowotworów Układu Moczowego Kierownik kliniki: dr hab. Tomasz Demkow
keywords
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testis, testicular cancer, late relapse, treatment
summary
- Aim of the study. The aim of this study is to present the experience of the Oncology Center in Warsaw in the treatment of late relapses of testicular cancer.
- Material and methods. A retrospective analysis was made of 1013 patients treated at our center between 1974 and 1996 for tumor of the testis. In 27 of 1013 patients (2,7%) late relapse, e.g. recurrence observed at least 2 years after complete remission of the primary tumor, was diagnosed. The frequency of late relapses was 3.6% for patients treated previously for seminoma, and 2.3% for those with nonseminomatous neoplasm.
- Results. Of 27 patients with late relapse, in 11 patients (41%) seminoma, and in 16 (59%) nonseminoma was diagnosed. The treatment of whole group consisted of cytostatics, combined with surgery in 6. and with radiotherapy in 8 patients (one of them underwent retroperitoneal lymphadenectomy before irradiation). In 21 of 27 patients (78%) complete remission after treatment of the recurrence was noted. In 4 patients (15%) we observed partial remission followed by progression of the disease. Progression during treatment appeared in 2 patients (2%). In 8 patients initial complete remission was followed by progression of the neoplastic disease. In general, durable remission was observed in 13 of 2 7 patients (48%). Twelve patients died.
- Conclusions. Late relapses of testicular cancer are rare {2,7% in our material), hi patients with primary seminoma the recurrences are more frequent than in nonseminoma group (3.6% and 2.3%. respectively). Increase of testicular tumor marker values is often associated with relapse. Because of the possibility of late recurrences, long-term follow-up after successful treatment of primary tumor is needed in this group of patients.
references
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correspondence
Pawel Wiechno
Centrum Onkologii - Instytut im. Marit Sklodowskiei-Curie
Klinikti Nowotworów Układu Moczowego
ul. Roentgena 5
02-781 Warszawa
lei/fiu: (0...22) 643 92 31
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