PTU - Polskie Towarzystwo Urologiczne
list of articles:

Immunohistochemical staining of cholecystokinin (CCK-8) in male genital tract of the rat in postnatal development (computer analysis of the morphological image)
Article published in Urologia Polska 2002/55/4.

authors

Bogdan Mi¶kowiak 2, Andrzej Limanowski 1, Małgorzata Partyka 1, Aneta Konwerska
1 Katedra i Zakład Histologii i Embriologii Akademii Medycznej w Poznaniu Kierownik katedry: prof, dr hab. Andrzej Łukaszyk
2 Katedra Optometrii i Biologii Układu Wzrokowego Akademii Medycznej w Poznaniu Kierownik katedry: prof, dr hab. Bogdan Mi¶kowiak

keywords

male genital tract, testis, epididymis, prostate, seminal vesicles, cholecystokinin (CCK-8), postnatal development, image computer analysis

summary

The nun of the study. The aim of this study is to establish presence, location and role of cholecystokinin (CCK-8) in the genital tract of
male rat in postnatal development. Material and methods. Location of cholecystokinin (CCK-8) in testes, epididymal ducts, seminal vesicles and abdominal prostates of the
rats were determined immunohistochemically from birth to sexual maturity. The intensity of the reaction in secretory cells was
estimated by computer programme, which showed optical density of the reaction. Results. CCK-8 was observed in a Golgi apparatus region of glandular cells of the prostate and in epididymal ducts in 20 and 35 day,
respectively. The immunoposilive reaction was seen in seminal vesicles in 35 day and was observed during examination time in all
cytoplasm of the epithelial cells. In stromal and gamctogenic region of the testis CCK-8-immunopositivc substances were not seen. Conclusions. Our results show the important influence of CCK-8 on a growth and differentiation of epididymal duct, seminal vesicles and
abdominal prostate.

references

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correspondence

Bogdan Mi¶kowiak
Katedra i Zakład Htsiologii i Embriologii AM
ul. ¦więcickiego 6
60-781 Poznań
tel (0-61) 86-99-181 w. 546
fax (0-61) 86-58-130
e-maih bmiskow@am.poznan.pl