PTU - Polskie Towarzystwo Urologiczne
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Blood loss after transurethral resection of the prostate following different methods of conservative therapies
Article published in Urologia Polska 2008/61/4.

authors

Roland Dadej
Indywidualna Specjalistyczna Praktyka Lekarska

keywords

prostate benign prostatic hyperplasia (BPH) conservative treatment electroresectio TUR-P – bleeding

summary

The aim of the study.
Evaluation of the blood loss in patients with benign prostatic hyperplasia (BPH) after transurethral resection
of the prostate (TUR-P) in regards to previously chosen conservative treatment method.

Materials and methods.
The group of 119 patients was evaluated. Patients formed homogenous population as regards to the
baseline laboratory test results. The size of the prostate was tested with transabdominal ultrasound scan (volume of the gland was
bigger in patients receiving finasteride therapy). The haemoglobin and haematocrit levels were measured before and after the surgery.
The study results were statistically analyzed.

Results.
In the patients on finasteride therapy prior to the TUR-P, the haemoglobin and haematocrit levels in the perioperative period
were considerably higher than those within the patient groups treated with alpha blockers or receiving no medication.

Conclusions.
Finasteride treatment in the patients’ preparation for the TUR-P markedly reduces the risk of perioperative bleeding, and
thus – minimizes the transfusion of blood derivative preparations risk. 5-alpha-reductase inhibitor may be taken into account as a preoperative
drug before the surgery in patients with BPH, or those who do not agree for blood transfusion or any blood derivatives.

references

  1. Gentens P, Van der Planken M, Augustijns J: Transurethral prostatectomy: a bloodspilling technique Acta Chir Belg 1986, 86 (6), 349-351.
  2. Kirollos MM, Campbell N: Factors influencing blood loss in transurethral resection of the prostate (TURP): auditing TURP. Br J Urol 1997, 80 (1), 111-115.
  3. de Campos Freire G, de Campos Pachelli L, Cordeiro P et al: Blood loss during and following transurethral resection. Prostate 1986, 8 (1), 87-92.
  4. Levin K, Nyren O, Pompeius R: Blood loss, tissue weight and operating time in transurethral prostatectomy. Scand J Urol Nephrol 1981, 15 (3), 197-200.
  5. Abrams PH, Shah PJ, Bryning K et al: Blood loss during transurethral resection of the prostate. Anaesthesia 1982, 37 (1), 71-73.
  6. Mackenzie AR: Influence of anaesthesia on blood loss in transurethral prostatectomy. Scott Med J 1990, 35 (1), 14-16.
  7. Miskowiak J, Frost J: Blood loss during transurethral resection of the prostate: Ugeskr Laeger 1996, 1, 158 (27), 3924-3927.
  8. Poulsen EU, Wedel P, Krarup T: Evaluation of blood loss and absorption of irrigating fluid in transurethral resection of the prostate. Ugeskr Laeger 1998, 27, 160 (31), 4528-4530.
  9. Oszlanczi J, Szabo M: Measuring blood loss during transurethral resections. Acta Chir Hung 1990, 31 (1), 69-73.
  10. Hahn RG: Influence of variations in blood haemoglobin concentration on the calculation of blood loss and volumetric irrigating fluid balance during transurethral resection of the prostate. Br J Anaesth 1987, 59 (10), 1223-1229.
  11. Sokeland J: Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome. BJU Int 2000, 86 (4), 439-442.
  12. Sieber PR, Rommel FM, Huffnagle HW et al: The treatment of gross haematuria secondary to prostatic bleeding with finasteride. J Urol 1998, 159 (4), 1232-1233.
  13. Hagerty JA, Ginsberg PC, Harmon JD, Harkaway RC: Pretreatment with finasteride decreases perioperative bleeding associated with transurethral resection of the prostate. Urology 2000, 55 (5), 684-689.
  14. Sandfeldt L, Bailey DM, Hahn RG: Blood loss during transurethral resection of the prostate after 3 months of treatment with finasteride. Urology 2001, 58 (6), 972-976.

correspondence

Roland Dadej
Indywidualna Specjalistyczna Praktyka Lekarska
Os. Rzeczypospolitej 6
61-397 Poznań
tel. kom. 501 516 005
rolandd@onet.eu